Case of the Quarter

How to submit Case of the Quarter

  March "Hemophagocytic Lymphohistiocytosis Secondary to T cell/histiocyte-rich Large B-cell Lymphoma"
Contributors: Katherine Devitt, M.D., Benjamin Chen, M.D., Ph.D., Hongbo Yu, M.D., Ph.D., Bruce Woda, M.D., Department of Pathology, University of Massachusetts Memorial Medical Center and University of Massachusetts Medical School, Worcester, MA
  September Pure Erythroid Leukemia Evolving from a Chronic Myeloproliferative Neoplasm
Please enjoy the newly designed Case of the Quarter available from the ASCP education store. This activity provides 1 AMA PRA Category 1 CMETM credit. Follow this link, and simply add the course to your cart, which is free for SH members, and process your free enrollment. Then log in to your SH account on the ASCP website at, and look for your new course under "My Learning Plan".
  December "Diagnosis: MonoMAC Syndrome"
Contributors: Frida Rosenblum, MD and Elizabeth A. Morgan, MD, Department of Pathology, Brigham and Women's Hospital, Boston, MA 20115
  August "Diagnosis: ACUTE MYELOID LEUKEMIA, NOS with MYC Amplification & Promyelocytic Differentiation"
Contributors: Daimon Simmons, MD, PhD, Paola Dal Cin, PhD and Frank C. Kuo, M.D., Ph.D., Department of Pathology, Brigham and Women's Hospital, Boston, MA 20115
Contributors: Jitakshi De, M.D. of Deepath Medical; Human Immune Monitoring Center, Palo Alto, CA; and Megan S. Lim, M.D., Ph.D., Department of Pathology, University of Michigan Hospital System, Ann Arbor, MI
  November "Multiple Anticoagulant-Dependent Pseudothrombocytopenia (MADPT)"
Contributors: Erin Quist, MD and Patricia Aoun, MD, MPH, University of Nebraska Medical Center, Omaha, Nebraska, USA
  August "Angioimmunoblastic T-cell lymphoma with EBV-negative clonal plasma cell proliferation"
Contributors: Alison R. Huppmann, MD & and Elaine S. Jaffe, MD, Laboratory of Pathology, Hematopathology Section, National Cancer Institute
  May "Pediatric Follicular Lymphoma, Low-Grade with Marginal Zone Differentiation"
Contributors: Jennifer A. Bennett, M.D. and Michael Bayerl, M.D., Milton S. Hershey Medical Center

  February "B-Cell Lymphoma and Histiocytic/Dendritic Sarcomas Coexisting: Two Case Reports"
Contributors: Jeffrey Petersen MD and Jonathan Said MD, UCLA Medical Cente

  November "IgG4-Related Lymphadenopathy"
Contributors: Kate Grimm, M.D. & Dennis P. O'Malley, M.D., Clarient Diagnostics/G.E. Healthcare, Aliso Viejo, CA
  August "Bone Marrow Involvement by Cystinosis"
Contributors: Roseann Wu, MD, MPH & Robert Hasserjian, MD, Massachusetts General Hospital, Department of Pathology, Boston, Massachusetts
  May "Peripheral T-cell lymphoma with aberrant expression of CD30, CD15, and CD20"
Contributors: Joo Y. Song, MD and Elaine S. Jaffe, MD, Laboratory of Pathology, Hematopathology Section, National Cancer Institute
  February "Concomitant BCR/ABL and JAK2V617F positive myeloproliferative neoplasms"
Contributors: Jen Hummel M.D. and Megan S. Lim M.D. Ph.D., Department of Pathology, University of Michigan, Ann Arbor, Michigan
  May "Hepatosplenic T-Cell Lymphoma"
Contributor: Dragos C. Luca, M.D., Department of Pathology, Children's Hospitals & Clinics of Minnesota, Minneapolis, Minnesota
  February "Amyloidosis with Associated Lymphoplasmacytic Neoplasm"
Contributors: Sara McClintock-Treep MD & Qian-Yun Zhang MD, PhD, University of New Mexico Health Sciences Center & Tricore Reference Laboratories, Department of Pathology, Albuquerque, New Mexico
  November "Chronic Myelomonocytic Leukemia-2 with Isolated Del(5q)"
Contributors: Adrian Padurean, MD, AmeriPath Milwaukee, Milwaukee, WI and Kurt Oesterling, MD, Oncology Alliance – Milwaukee West, Wauwatosa, WI
  August "Precursor B-Cell Acute Lymphoblastic Leukemia and Histiocytic Sarcoma"
Contributors: Joseph D. Khoury, MD, Department of Pathology, Nevada Cancer Institute and Quest Diagnostics, Las Vegas, NV and Rebecca McClure, MD, Department of Pathology, Mayo Clinic, Rochester, MN
  May "Sézary Syndrome with Aberrant Expression of CD34 by Flow Cytometric Analysis"
Contributors: Arand Pierce M.D. and Qian-Yun Zhang M.D., Ph.D., Department of Pathology, University of New Mexico, School of Medicine, Albuquerque, NM
  February "Florid Progressive Transformation of Germinal Centers with Expanded CD4+CD8+ Double-Positive T-Cell Population"
Contributors: Emily Howard MD, PhD, University of Arkansas for Medical Sciences & Arkansas Children's Hospital and Robert B. Lorsbach, MD, PhD, University of Arkansas for Medical Sciences, Little Rock, AR
  November "Composite Lymphoma, Presenting As B-Cell Follicular Lymphoma and Classical Hodgkin Lymphoma, in a Patient with a History of Methotrexate Therapy"
Contributors: Michel R. Nasr, M.D., Brian K. Link,M.D., and Vishala T. Neppall, M.D. - University of Iowa, Iowa City, Iowa
  August "IgD-Positive Nodular Lymphocyte Predominant Hodgkin Lymphoma (NLPHL)"
Contributor: Dennis P. O'Malley, M.D - Clarient Diagnostics, Inc., Aliso Viejo, CA
  May "Precursor B-Cell Lymphoblastic Leukemia with Marked Eosinophilia"
Contributors: Andrew Laramore, M.D. and Cherie H. Dunphy, M.D. - Department of Pathology and Laboratory Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
  February "Extramedullary Blast Transformation of CML at Initial Presentation"
Contributors: Neerja Vajpayee M.D., Constance Stein PhD, Bernard Poiesz, and Robert E.Hutchison, M.D. - Department of Pathology, State University of New York (SUNY), Upstate Medical University, Syracuse, NY
  November "Acute Megakaryoblastic Leukemia in a Patient with a History of Breast Carcinoma and Polycythemia Vera"
Contributors: Elizabeth Wey, M.D. and Mary Ann Thompson, M.D., Ph.D. - Department of Pathology, Division of Hematopathology, Vanderbilt University Medical Center, Nashville, TN
  August "Inflammatory Pseudotumor-Like Follicular Dendritic Cell Tumor of the Spleen"
Contributor: Mohammad A. Vasef, M.D. - Department of Pathology, University of New Mexico Health Sciences, Albuquerque, New Mexico
  May "Autoimmune Lymphoproliferative Syndrome"
Contributor: Michele E. Paessler, D.O. - Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine
  February "Intravascular Large B-Cell Lymphoma"
Contributors: David T. Yang, MD and Sherrie L. Perkins, MD, PhD - Department of Pathology, The University of Utah, Salt Lake City, Utah
  November "Follicular Lymphoma Arising in Intrahepatic Splenosis Mimicking Hepatocellular Carcinoma in a Patient with Chronic Hepatitis C Virus Infection and Cirrhosis"
Contributors: Patricia Aoun MD, MPH and Hina Naushad MD - Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska
  August "Refractory Anemia with Ringed Sideroblasts (RARS) Associated with (Marked) Thrombocytosis and Plasma Cell Dyscrasia (PCD) (Smoldering Myeloma)"
Contributors: Antonio E. Martinez M.D. and Cherie H. Dunphy M.D. - Department of Pathology and Laboratory Medicine, Division of Hematopathology, University of North Carolina
  May "Follicular Lymphoma of the Ocular Adnexa in a Child"
Contributors: Rania M. Seliem, M.D. and Judith A. Ferry, M.D. - Department of Pathology Massachusetts General Hospital and Harvard University Medical Center Boston, Massachusetts
  February "Primary Effusion Lymphoma in an HIV-negative Patient"
Contributors: Brian Webber, M.D. and Jeannine T. Holden, M.D. - Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA
  November "Recurrent Squamous Cell Carcinoma and Follicular Lymphoma Presenting as a Collision Tumor"
Contributors: David A. Wada, M.D., Neeraj Agarwal, M.D., and Megan S. Lim, M.D., Ph.D., FRCP(C) - Department of Pathology, and the ARUP Institute for Clinical and Experimental Pathology, University of Utah, Salt Lake City, Utah


"Mycosis Fungoides, Granulomatous Slack Skin Subtype"
Contributor: Jennifer E. Blankenship, M.D. and Marsha C. Kinney, M.D. -  
University of Texas Health Science Center at San Antonio

  May "Hepatosplenic T-cell Lymphoma"
Contributor: Charles W. Ross - Department of Pathology, University of Michigan Medical School - Ann Arbor, Michigan
  February "Coexistent Chronic Eosinophilic Leukemia and T-lymphoblastic Lymphoma (8p11-12 Stem Cell Syndrome)"
Contributors: Xiaoying Qiao, Serhan Alkan, Milind Velankar and Ameet R. Kini - Department of Pathology, Loyola University Medical Center - Maywood, Illinois
  November "Follicular Dendritic Cell Tumor Mimicking GI Stromal Tumor"
Contributor: Dennis P. O'Malley - Department of Pathology and Laboratory Medicine, Division of Hematopathology - Indiana University - Indianapolis, Indiana
  August "Severe Congenital Neutropenia (Kostmann Syndrome)"
Contributor: John Kim Choi - Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, PA
  May "Symptomatic Parvovirus B19-induced Anemia in a Patient with Previously Undiagnosed Band 3 Protein Defect-associated Hereditary Spherocytosis "
Contributors: Sarah Navina and Phuong L. Nguyen - University of Minnesota Medical School - Minneapolis, Minnesota; Kathy Frey - Fairview-Southdale Medical Center - Edina, Minnesota
  February "Inflammatory Pseudotumor of the Liver "
Contributors: Brent Tan and Daniel A. Arber - Stanford University Medical Center
  November "Secondary Acute Myeloid Leukemia Shortly Following Chemotherapy for Angioimmunoblastic T-Cell Lymphoma "
Contributors: Young S. Kim, Yibin Zhang, Qin Huang - City of Hope National Medical Center - Duarte, California
  February "Combined Variable Immunodeficiency"
Contributor: Vishnu V. B. Reddy - University of Alabama at Birmingham Medical Center - Birmingham, Alabama
  November "Fanconi's Anemia"
Contributor: Sharon M. Geaghan - Lucile Salter Packard Children's Hospital at Stanford - Palo Alto, California
  August "Body cavity based lymphoma"
Contributor: Jonathan Said - Cedar Sinai Medical Center - Los Angeles, California

  May "Langerhans cell histiocytosis"
Contributors: Joseph A. DiGiuseppe and Risa B. Mann - The Johns Hopkins Hospital - Baltimore, Maryland

  February "Marginal zone lymphoma with transformation to large cell variant"
Contributor: Nancy S. Rosenthal - University Hospital of Cleveland - Cleveland, Ohio

  November "Composite lymphoma"
Contributors: Kamilia S. Rizkalla, Kang Howsom-Jan, R.M. Barr, University Hospital, London, Ontario, Canada
  August "T cell prolymphocytic leukemia"
Contributors: Susan Wheaton, William Finn, Northwestern University Medical School, Chicago, Illinois

  May "Small lymphocytic lymphoma with Reed-Sternberg cells"
Contributors: John F. Lombardo, Sherrie L. Perkins, Thomas A. Piira, Carl, R. Kjellberg, University of Utah Medical Center, Salt Lake, City, Utah

  February "Extramedullary lymphoblastic transformation (T-immunophenotype) of Philadelphia chromosome positive chronic myelogenous leukemia"
Contributors: John D. Feczko, Richard Neiman, Indiana Univeristy Medical School, Indianapolis, Indiana

  November "Philadelphia Chromosome positive essential thrombocythemia, detected by fluorescence in situ hybridization (FISH)"
Contributor: Russell K. Brynes, City of Hope National Medical Center, Duarte California




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